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The episode finishes with everyone enjoying the party. Prevalence of cardiovascular disease and cancer during cross-sex HRT in a large cohort of trans persons: Exp Clin Endocrinol Diabetes. Conflicts of interest The authors declare they have no conflicts of interest. Current literature suggests HT is safe when followed carefully for certain risks. As seen in an estrogen-dependent transsexual. Induction of insulin resistance by androgens and estrogens.

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While these provide clues to effects of transgender HT, there is a strong need for future research of greater cohort size to be undertaken in order to address this critical gap. There are three case reports of MTF individuals with meningioma while on estrogen HT involving intracranial [41] , tuberculum sellae [42] , and an olfactory groove locations [43] , and one case report of a pituitary adenoma [44]. Estrogen therapy may be safe even for MTF adults who have hypercoagulable mutations Estrogen therapy in transgender adults may be safe even in the presence of hypercoaguable gene deficiencies. The study authors found no clear link between testosterone and FEUA. Hypercoaguable risk factors, including the use of a thrombogenic estrogen, ethinyl estradiol, have been associated with many of the cases of reported VTE, and as such the risk of these adverse events may continue to decline as the usage of this drug diminishes [3]. Body composition, volumetric and areal bone parameters in male-to-female transsexual persons. Breast cancer in a trans-sexual man receiving hormone replacement therapy.

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Nevertheless, an earlier study reported that while self-reported decreased sexual desire was experienced in one-third of a group of 62 MTF individuals, this level was similar to a group of pre-menopausal female controls [66]. No competing financial interests exist. Leptin, ghrelin, and adiponectin evaluation in transsexual subjects during hormonal treatments. The primary concern among MTF individuals on estrogen therapy is the possibility of developing thrombogenic complications 2 , 3 , 4 , 5 , 6 , 7. Such a role has been outlined in previous literature [9].

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